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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK1IP1
All Species:
35.15
Human Site:
T146
Identified Species:
59.49
UniProt:
Q9NWT1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWT1
NP_060376.2
392
43964
T146
L
S
V
G
T
D
K
T
L
R
T
W
N
L
V
Chimpanzee
Pan troglodytes
XP_518863
393
44017
T147
L
S
V
G
T
D
K
T
L
R
T
W
N
L
V
Rhesus Macaque
Macaca mulatta
XP_001087458
392
43967
T146
L
S
V
G
T
D
K
T
L
R
T
W
N
L
V
Dog
Lupus familis
XP_535884
391
43743
T148
L
S
V
G
T
D
K
T
L
R
T
W
N
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCE5
382
42097
T146
L
S
V
G
T
D
K
T
L
R
T
W
N
L
I
Rat
Rattus norvegicus
NP_001032433
382
42216
T146
L
S
V
G
T
D
K
T
L
R
T
W
N
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514604
358
39493
W129
T
D
K
T
L
R
T
W
N
L
I
E
G
R
S
Chicken
Gallus gallus
Q5ZKU8
369
41214
T139
L
S
V
G
T
D
K
T
L
R
T
W
N
L
V
Frog
Xenopus laevis
Q68FJ6
363
40513
G133
S
L
S
I
H
P
S
G
K
L
A
L
S
V
G
Zebra Danio
Brachydanio rerio
Q6TNS2
368
40882
P138
V
T
S
L
S
V
H
P
S
G
K
L
A
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181466
538
58474
T150
L
S
V
S
K
D
K
T
L
R
T
W
N
L
L
Poplar Tree
Populus trichocarpa
XP_002318775
332
35851
S103
S
F
P
R
N
L
L
S
A
S
A
D
G
S
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176683
345
37437
D116
D
G
S
V
A
I
F
D
T
D
P
F
V
L
L
Baker's Yeast
Sacchar. cerevisiae
P20484
468
53654
S226
I
S
V
S
D
D
H
S
I
R
L
W
N
L
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.1
85.4
N.A.
72.4
75.2
N.A.
65
63
60.4
53
N.A.
N.A.
N.A.
N.A.
27.7
Protein Similarity:
100
99.7
97.6
92.8
N.A.
83.9
83.4
N.A.
76.5
78.5
75
69.6
N.A.
N.A.
N.A.
N.A.
44.8
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
0
100
0
6.6
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
13.3
26.6
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
26.2
N.A.
N.A.
27
20.9
N.A.
Protein Similarity:
46.1
N.A.
N.A.
47.9
37.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
46.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
15
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
8
65
0
8
0
8
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
50
0
0
0
8
0
8
0
0
15
0
8
% G
% His:
0
0
0
0
8
0
15
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
8
0
0
8
0
8
0
0
0
8
% I
% Lys:
0
0
8
0
8
0
58
0
8
0
8
0
0
0
0
% K
% Leu:
58
8
0
8
8
8
8
0
58
15
8
15
0
79
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
0
8
0
0
0
65
0
0
% N
% Pro:
0
0
8
0
0
8
0
8
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
8
0
0
0
65
0
0
0
8
0
% R
% Ser:
15
65
22
15
8
0
8
15
8
8
0
0
8
8
15
% S
% Thr:
8
8
0
8
50
0
8
58
8
0
58
0
0
0
0
% T
% Val:
8
0
65
8
0
8
0
0
0
0
0
0
8
8
50
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
65
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _